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Sulfoximidations of Benzylic C-H bonds by Photocatalysis.
| Title | Sulfoximidations of Benzylic C-H bonds by Photocatalysis. |
| Publication Type | Journal Article |
| Year of Publication | 2018 |
| Authors | Wang H, Zhang D, Bolm C |
| Journal | Angewandte Chemie (International ed. in English) |
| Volume | 57 |
| Pagination | 5863-5866 |
| Date Published | 5 |
| ISSN | 1521-3773 |
| Abstract | An efficient photocatalytic functionalization of compounds with benzylic C-H bonds by sulfoximidation in visible light is described. The mild reaction conditions allow the use of a broad array of substrates, including diarylmethane, alkyl arenes, arylacetonitrile, 2-arylacetate, and alkynyl aryl methanes. The sulfoximidation process is highly chemoselective and leads to the corresponding sulfoximines in generally good yields. Mechanistic investigations suggested the intermediacy of sulfoximidoyl radicals. |
| DOI | 10.1002/anie.201801660 |